The modern healthcare system around the world is experiencing a deep systemic crisis. Traditional "reactive" medicine, which begins to act only after the first clinical symptoms of the disease appear (most often in its late or even irreversible stages), demonstrates its financial and therapeutic inability to combat the pandemic of chronic non-communicable diseases.

Type 2 diabetes mellitus (T2DM) is a growing global health problem that is closely related to the obesity epidemic. It is one of the most common non-communicable diseases in the world, characterized by disorders of carbohydrate, lipid and protein metabolism, and arises from impaired insulin secretion, cellular resistance to insulin or a combination of these factors.

Most of us have tried to lose weight at least once in our lives. We count calories, weigh every serving, give up our favorite foods, and exhaust ourselves with strict diets. But why is it that for some people, just looking at a dessert is enough to gain weight, while others can eat cake at night and stay slim?