Ediens Shares Results of a Two-Year Study on the Microbiome and PTSD: 16 Biomarkers and a Personalized Correction Algorithm

Sep 25

2 min read

Nearly 300 participants. Several lines of research. One big question: what happens in the body of a person living with PTSD? Over the past two years, the Ediens team at Uzhhorod National University has studied the links between the gut microbiome, immune responses, biochemical markers, and psychological well-being.

We worked with military personnel and internally displaced people, compared findings across groups, and used multiple independent methods to verify our observations. We identified 16 potential biomarkers for the further development of a PCR-based test. At the same time, we developed an algorithm for personalized interventions, approaches to selecting pharmabiotic formulations, and prototypes of functional food products.

Who Took Part and How the Study Was Conducted

Nearly 300 people took part in the study — military personnel and internally displaced people facing elevated chronic stress. The team compared results across groups and verified every observation using several independent laboratory methods to ensure reliable results.

Key Findings of the Two-Year Study

16 Potential PTSD Biomarkers

Researchers identified 16 indicators statistically linked to PTSD that could form the basis of an objective lab-based PCR test — alongside psychological questionnaires.

A Personalized Correction Algorithm

Based on an individual's biomarker profile, the algorithm suggests exactly which microbiome correction approach to apply in each case.

Selecting Pharmabiotic Formulations

The team defined approaches for selecting specific probiotic/pharmabiotic strains and combinations based on the microbiome imbalances identified.

Functional Food Prototypes

The first prototypes of functional food products supporting the microbiome and psychological well-being were developed as part of the personalized approach.

How This Is Already Being Applied

While the PCR test system and functional food products are still under development, Ediens has already built part of these findings into its pharmabiotic lineup. ‘Metabolic Anti-Stress,’ in particular, is built on the same principle — supporting the gut-brain axis to reduce stress levels and restore psycho-emotional balance.

Pharmabiotic ‘Metabolic Anti-Stress’

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What's Next

The next step is to bring the research to a full PCR test system that can laboratory-confirm PTSD microbiome markers, as well as to test the functional food prototypes in clinical settings.

Frequently Asked Questions

What is a PCR test system for PTSD, and why is it needed?

It's a laboratory test that identifies specific microbial and biochemical markers linked to PTSD. Unlike psychological questionnaires, it provides objective data that can be used for diagnosis and monitoring a patient's condition.

Who took part in the Ediens study?

Nearly 300 people — military personnel and internally displaced people. The team compared results across groups and verified observations using several independent methods over two years.

What is the personalized microbiome correction algorithm?

It's a system that, based on an individual's biomarker profile, suggests exactly which pharmabiotics, probiotics, or dietary approaches a specific person needs to restore microbiome balance and reduce stress load.

Can you already benefit from this research?

Partly, yes. While the PCR test and functional food products are still being refined, the research principles are already built into Ediens' pharmabiotics, including 'Metabolic Anti-Stress,' which supports the gut-brain axis.